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In gynecologic oncology, particularly in cervical and endometrial cancers, curcumin may be integrated into combination regimens with chemotherapy, radiotherapy, or hormonal therapies to potentiate treatment responses, mitigate therapy-induced inflammation, and potentially overcome drug resistance through modulation of key signaling pathways such as NF-B, STAT3, and PI3K/Akt

Herbrich S, Ruvolo P, Ruvolo V, Baggerly K, Al-Atrash G, Andreeff M , Konopleva M

Through its ability to affect miRNA expression and mRNA targets as well as epigenetic modulation, GT catechins contribute to the inhibition of prostate carcinogenesis

Our results suggest that the pharmacological inactivation of HIF-1, CREB, p53 or NRF2 could be beneficial for the treatment of obesity and type 2 diabetes in humans