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Clinical challenges and mitigation strategies Core clinical and research challenges With the widespread clinical use of platinum-based chemotherapeutics, long-term in vivo platinum accumulation has emerged as a critical yet underrecognized clinical challenge, serving as the core toxicological driver of impaired long-term quality of life and adverse health outcomes in cancer survivors

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This suggests that an intermediate host between bats and humans may not have been necessary after all

Antonioni A, Raho EM, Lopriore P, Pace AP, Latino RR, Assogna M, Mancuso M, Gragnaniello D, Granieri E, Pugliatti M, et al

Chen Z, Yang B, Yan Z, Song E, Song Y