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FIGURE 2 Drug Delivery Systems for Neurotrophic Factor Therapy Neurotrophic factors, and glial cell line-derived neurotrophic factor (GDNF) in particular, have been regarded as one of the most promising molecules for PD

All of these events contribute to the development of diabetic microvascular and macrovascular complications, suggesting that the sources of reactive oxygen species and the signaling pathways that they modify may represent important therapeutic targets

doi: 10.7554/eLife.63326 16 HeydtQLarrueCSalandEBertoliSSarryJEBessonAet al

Any compromise to the seal allows moisture and oxygen ingress that accelerates degradation

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