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Gliadins, rich in glutamine and proline, and resistant to digestion by human proteases, are the trigger factor for celiac disease in genetically predisposed individuals [139]

J Agric Food Chem 66(18):46304637 Zhou F, Xu T, Zhao Y, Song H, Zhang L, Wu X, Lu BJFH (2018b) Chitosan-coated liposomes as delivery systems for improving the stability and oral bioavailability of acteoside

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Several factors influence this process: enterohepatic cycling in adults, driven by condition like bile salt malabsorption or prolonged intestinal transit time, promotes the recycling of unconjugated bilirubin, increasing its hepatic load and biliary secretion