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Untargeted lipidomics analysis of synovial fluid and serum from RA patients across various clinical stages, ranging from preclinical to active and sustained phases, showed that despite normal erythrocyte sedimentation rate and CRP at pre-clinical stages, the lipidomic profile of preclinical RA joint fluid closely resembled that of active RA (191)

[91] analyzing European Medicine Agency database of suspected adverse drug reaction, noticed 143 cases regarding LC

10.1371/journal.pone.0183491 223 YuD.ChengT.LiuT.XuW.LiuD.DaiJ.et al (2024)

Conclusions In summary, while further research is needed to elucidate the biological mechanisms underlying these observations, this study employed a systematic approach, providing novel evidence that higher intake of SAAs/aromatic AAs is independently associated with increased incidence of T2D, whereas higher dietary glutamine intake appears to be associated with reduced T2D incidence