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Copper transporter deficiency in ATP7A-deficient Menkes disease-mimicking fibroblasts is associated with mitochondrial redox imbalance that contribute to toxicity, related to copper overload [3]

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However, free G-6-P is difficult to pass through the cell membrane due to its negative charge, we employed the well-established liposome technology to encapsulate G-6-P (G-6-P-liposome), thereby facilitating its cellular uptake (Supplementary Fig