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Recently, the aberrant methylation of the Protein Kinase Y-Linked ( PRKY ) gene, located on the Y-chromosome, has emerged as a promising and valuable diagnostic marker for the early detection of PRAD [173]

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[DOI] [PubMed] [Google Scholar] 16.Greene AS, Lombard JH, Cowley AW Jr., Hansen-Smith FM

Moreover, mice lacking both the Arx and the Pax4 genes display significant shrinkage of both - and -cell lineages and die neonatally because of lethal hyperglycemia 6