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10.1038/nm.2618 318 RussoA.ScardigliR.La ReginaF.MurrayM

Moreover, MSNs were used as core substrates for further materials growth, or as the carrier shell coating on other functional nanostructures including those particles mentioned above

By enhancing ER protein-folding capacity, reducing the accumulation of misfolded proteins, and activating adaptive signaling programs, the UPR allows cancer cells to survive and proliferate in hostile microenvironments that would otherwise compromise cellular viability