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The mechanisms of bacterial antibiotic resistance, such as efflux pumps, antibiotic-modifying enzymes and gene mutations, are well investigated, but they are limited to planktonic bacteria (Sun et al., 2020

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Lian Leng Low, [email protected] Specialty section: This article was submitted to Family Medicine and Primary Care, a section of the journal Frontiers in Medicine Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers