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Although effective, these protocols were lengthy, costly, and at times impracticalespecially for patients needing intermittent therapy, as serial desensitization was required for temporary tolerance for each antibiotic course

Umbrella trials Type of clinical trial that evaluates multiple treatments or interventions simultaneously within the same overarching trial framework (for example, testing multiple novel therapies in a single trial in patients with Crohns disease)

Since AILI patients have the potential to develop chronic liver injury at a later stage, patients need to be followed up for at least 12 months after treatment

10.1080/19490976.2021.1990827 Gut Microbes

The enzyme 5-LOX can act on 5-HETE to generate an unstable epoxide leukotriene A4 (LTA4), which can serve either as an intracellular intermediate in the synthesis of leukotriene B4/C4 (LTB4 and LTC4)