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This allowed a variety of boronic acids to be coupled to a model cysteine-linked aryl iodide, with the benefit that even hydrophobic moieties could be transferred to the protein surface due to the water-solubilizing effect of the boronate group

SVCT1 is found mostly in epithelial tissues (e.g., small intestine and proximal tubule of the nephron), where the transport of ascorbate is greater than that required by the cells

An experimental analysis of a group of cancer cell lines with low and high GPX4 expression demonstrated that inhibiting DHODH could induce ferroptosis in tumor cells with low GPX4 expression while enhancing ferroptosis resistance in cancer cells with high GPX4 expression

Further trials should conduct better randomization and blinding procedures, recruit more participants, and provide adequate reporting

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