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A., Spires-Jones, T

A., Rajan, V., Miller, C

The rationale for conducting the pilot study was to obtain first feasibility and safety/tolerability data to determine if it would be ethically acceptable to randomize visually impaired patients (a vulnerable group) to possibly receive the experimental treatment and not a standard donor cornea and surgery when available, as would be required for a future randomized controlled trial

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3 However, a 2005 meta-analysis including only high-quality trials did not detect a significant effect in symptomatic relief of plantar fasciitis