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PTSD + MDD ( n = 18) and PTSD only ( n = 7) participants did not differ in circulating levels of MMP-9 ( p = 0.282), TIMP-1 ( p = 0.394), nor TIMP-2 ( p = 0.784)

Cell viability was normalised to DMSO (vehicle) treated cells

T.LykkesfeldtJ.LiuJ.WehrC

Inhibition of TGF- or its downstream effectors by large molecule ligand traps and antisense oligonucleotides are novel therapeutic approaches being explored today [45]