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Furthermore, we observed a reduction of intracellular ROS in metZ upon methionine supplementation at pH 7.2, while this effect was less pronounced at pH 5.5 (Fig

Since selenium deficiency can disturb normal CV homeostasis, lack of selenium contributes to the pathogenesis of multiple CVDs, including myocardial infarction, heart failure, coronary heart disease, and atherosclerosis (207)

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These conditions share common pathologies, including progressive loss of neurons, oxidative stress, impaired DNA repair, and abnormal protein aggregation

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