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Sirt3 is required for HSC self-renewal under stress conditions by suppressing reactive oxygen species (ROS) and ameliorating loss of HSC quiescence and death 30

10.1523/JNEUROSCI.0494-21.2021 398 WuY.SunX.SongB.QiuX.ZhaoJ

Its dense network of peripheral nerve endings provides the anatomical basis for localized neurotransmitter release and spatially restricted neuromodulation