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Patients should seek emergency medical help (call 999) if they experience: Difficulty breathing, wheezing, or throat tightness Swelling of the face, lips, tongue, or throat (angioedema) Widespread urticarial rash (hives) developing rapidly Dizziness, fainting, or rapid heartbeat suggesting anaphylaxis These symptoms typically occur within minutes to hours of administration, most commonly with injectable preparations

Simon, A., Wegrowski, Y., Bontemps, Y., & Maquart, F

Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity

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