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A second obstacle is that redox-active metals, such as iron, copper, and manganese can engage in Fenton-type chemistry in the presence of oxygen and produce potentially damaging reactive oxygen species

Furthermore, an inverse relationship exists between GPX3 activity and the rate of eGFR decrease in patients with diabetes and advanced CKD

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We then addressed the ability of the engineered IgG subclasses to engage C1q, which revealed that IgG2 turned into a complement activator that could mediate CDC against CD20 low WSU-NHL cells (Fig

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