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Gut microbiota and multiple sclerosis MS is a chronic immune-mediated disease of the CNS characterized by inflammation, demyelination, and neurodegeneration

When delivered intravenously, glutathione reaches the bloodstream directly, bypassing the gut to deliver higher bioavailability and immediate cellular absorption

Figure 2 2.1 Iron homeostasis Iron is crucial for preventing lipid peroxidation in the process of ferroptosis ( The skin serves multiple functions, acting as a protective barrier against external physical, chemical, and biological factors, while also playing roles in temperature regulation, sensory transmission, and immune responses ( However, an imbalance of iron ions, whether in excess or deficiency, can have adverse effects on the skin microenvironment

For the metabolites retained after filtering, values below the LOD were replaced with the minimum detected value, while values above the LOD were replaced with the maximum detected value for each respective variable

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