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Wan et al., Engineering multienzyme-mimicking covalent organic frameworks as pyroptosis inducers for boosting antitumor immunity

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3.3.1 Antioxidant activity Substances such as shikonin, alkanin, lawsone, emodin, epigallocatechin-3-gallate, and ellagic acid, along with certain herbal extracts, act as potent antioxidants by scavenging reactive oxygen species (ROS), inhibiting lipid peroxidation, and enhancing the activities of intracellular antioxidant enzymes, including superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px)

[29] The thiol group also has a high affinity for heavy metals, so that proteins containing cysteine, such as metallothionein, will bind metals such as mercury, lead, and cadmium tightly

When respiratory inflammation occurs, these mucins form thick, viscous plugs that are incredibly difficult to clear, leading to chronic congestion and shortness of breath