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Researchers should consult the primary literature and follow institutional protocols, including appropriate handling given copper's toxicity profile at higher concentrations

E.SudderthJ.YueY.ZiaA.GlassD.et al (2016)

These findings collectively suggest that low-dose sirolimus possesses a favorable risk-benefit ratio in RA patients across varying disease activity states, supporting its potential as an immunomodulatory adjunct in RA management