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This could reduce the protection that these proteins provide to dopaminergic neurons, increasing their vulnerability to oxidative stress damage (129, 220)

Managing Oxidative Stress Rapid changes in metabolism can sometimes increase the production of free radicals

N-acetyl-L-cysteine increases acute graft-versus-host disease and promotes T-cell-mediated immunity in vitro

In a multicenter, randomized, doubleblind, placebocontrolled phase 2 study (ClinicalTrails.gov Identifier: NCT01119833), Rivipansel showed clinical and meaningful reductions in multiple measures of VOC compared with those receiving standard of care treatment (Telen et al., 2015)

Isolation of an orally active insecticidal toxin from the venom of an Australian tarantula (Table S1)