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Description

It is believed to be effective in treating various skin conditions, including acne, eczema, and psoriasis

D.PrietoM.et al (2014)

By analyzing the cryo-EM structure, we noticed that the carbon ortho to the aldehyde (R2) is close to multiple residues, indicating the potential for substituents at this position (e.g., methyl, hydroxy, methoxy) to introduce a steric clash or sterically hinder the interaction between the C326 side chain and the aldehyde warhead

No other states require such stringent testing

Dermatological evidence indicates that melasma affects approximately 90% of the global female population at some point during their lifetime, with particularly high prevalence in skin phototypes III through VI