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73 IL-6 activates neutrophils, causing neutrophil infiltration at the inflammatory sites, inducing neutrophils to release elastase and various oxygen free radicals, destroying alveolar surfactants, increasing pulmonary vascular permeability and inducing pulmonary oedema

This dual action targets adipose tissue directly through the beta-3 adrenergic receptor pathway

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Although there was a clear trend for a higher Firmicutes : Bacteroidetes ratio in the WD control group relative to the LD control group, this difference did not rise to the level of statistical significance