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Mahoney SA, Venkatasubramanian R, Darrah MA, Ludwig KR, VanDongen NS, Greenberg NT, Longtine AG, Hutton DA, Brunt VE, Campisi J, Melov S, Seals DR, Rossman MJ, Clayton ZS

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If the temperature dropped to 0-2C but the solution did not freeze, it is fine, simply adjust the refrigerator setting

In AD, however, elevated brain iron drives microglia toward a ferroptosis-prone state, marked by upregulated heme oxygenase-1 and enhanced release of inflammatory mediators like IL-1 (140, 141)