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Paeoniflorin attenuates neuroinflammation and dopaminergic neurodegeneration in the MPTP model of Parkinsons disease by activation of adenosine A1 receptor

4.2 Oxidative stress and mitochondrial dysfunction Renal energy metabolism depends heavily on oxidative phosphorylation, and in CKD, mitochondrial dysfunction and oxidative stress form a vicious cycle that exacerbates tissue injury

demonstrated that treating human neuroblastoma cells (SH-SY5Y) and murine primary cortical neurons with sodium thiosulfate, a substrate for TST and a donor of H 2 S, significantly elevated intracellular thiosulfate levels and moderately increased the concentration of GSH [55]

After staining, the pellet is washed for 30 min in PBST

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