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For information on risks and side effects, read the package leaflet and ask your doctor or pharmacist

Ethics declarations Ethics approval and consent to participate Following local regulations, the protocol gained ethical and research approval from the local ethical scientific committee of the faculty of medicine (FMASU MS 239/2019)

Methylmalonic acid is a sensitive biomarker used to diagnose vitamin B12 deficiency, especially in borderline cases

Response: We acknowledge the commenters' recommendation to implement the proposed cost measure exclusion policy earlier than we proposed

Mitochondrial transfer/transplantation: an emerging therapeutic approach for multiple diseases