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Fariello RM, Del Giudice PT, Spaine DM, Fraietta R, Bertolla RP, Cedenho AP

J Nanosci Nanotechnol 16:75997605 Jadhav V, Ray P, Sachdeva G, Bhatt P (2016) Biocompatible arsenic trioxide nanoparticles induce cell cycle arrest by p21 WAF1/CIP1 expression via epigenetic remodeling in LNCaP and PC3 cell lines

In mitochondria, THF is imported via a mitochondrial folate transporter and converted into 5,10-methylene-THF by serine hydroxymethyltransferase 2 (SHMT2), which oxidizes serine to glycine while transferring a one-carbon unit to THF [15]

Once damaged, alveolar epithelial cells are able to secrete the cytokines IL-6, TNF-, and various chemokines such as CXCL1 and CXCL2 to alter the inflammatory cells [34, 35]