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10.1016/s0009-9120(99)00022-3 105 SeverA

Researchers have known about some peptides for decades, and dozens have been turned into safe and effective drugs

This is the key advantage, and it is why sublingual delivery can achieve bioavailability rates dramatically higher than oral swallowing

What to avoid: High-potency exfoliants and prescription-strength retinoids, like glycolic acid peels, products with salicylic acid, and Tretinoin, are not appropriate for the periocular zone unless specifically formulated for it

This makes them the commonly discussed for digestive support because it contacts the gastrointestinal lining