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Down-regulated peroxisome proliferator-activated receptor (PPAR) in lung epithelial cells promotes a PPAR agonist-reversible proinflammatory phenotype in chronic obstructive pulmonary disease (COPD)

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Mutations of ARID1A, an epigenetic regulator, in colorectal cancer patients were found to confer resistance to cetuximab rather than bevacizumab, with a relation to the EGFR/MAPK pathway (90)