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Sub-families of ABC transporters particularly MDR1 can bestow resistance to cytotoxicity and targeted chemotherapy and also have a significant functional transport role in BBB and BCSFB

Biosens Bioelectron 112217 Chen L, Qu G, Zhang C et al (2013) Quantum dots (QDs) restrain cervical carcinoma HeLa cell proliferation through inhibition of the ROCK-c-Myc signaling

Figure 6 3.4 Integrated analysis of the RNA-seq and metabolome data of oat leaves The DEGs and DAMs from the same group were mapped onto the KEGG pathway database to elucidate the associations between genes and metabolites

Beyond its anti-ferroptotic role, AB4 exerts multimodal effectsparticularly in combating inflammationthrough this RAGE-Nrf2 axis

In the eye field, 24 hours after retinal ischemiareperfusion, key indicators of ferroptosis, such as lipid peroxidation and the downregulation of GPX4, rise in tandem with apoptosis markers, including cleaved caspase-3 and TUNEL-positive cells (132)