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Importantly, when polyphenols and topoisomerase II inhibitors were combined, it was possible to induce a synergistic decrease in cell proliferation (measured as ATP levels), cell-cycle arrest and induction of apoptosis in leukaemia cell lines

[DOI] [PubMed] [Google Scholar] Mathialagan S., Bi Y.A., Costales C., Kalgutkar A.S., Rodrigues A.D., Varma M.V.S

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Iron and ferritin The most important protein in the body involved in normal iron metabolism is ferritin