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doi: 10.1016/S1474-4422(21)00030-2 248 DingXSGaoLHanZEleuteriSShiWShenYet al

There is a clear need for alternative treatments prior to surgery that [] slow or reverse the progression of intervertebral disc degeneration, said Jiangang Shi, professor in the Department of Orthopedic Surgery in Changzheng Hospital from Navy Medical University and co-lead author of the study published in Advanced Biology

It is widely believed that CR decreases mTORC1 signaling, which would result in the activation of autophagy while reducing overall biosynthesis, decreasing protein translation as well as lipid synthesis 27

Decreased gene expression of endothelial nitric oxide synthase in newborns with persistent pulmonary hypertension

Cooke MS, Evans MD, Dizdaroglu M, Lunec J (2003) Oxidative DNA damage: mechanisms, mutation, and disease