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10.1186/1756-0500-5-546 27 HeH.LiX.YuH.ZhuS.HeY.KomatsuK.et al (2019)

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A double-blind, placebo-controlled trial of ruxolitinib for myelofibrosis

[] It is not surprise that the upstream positive (e.g., SIRT1, [] Akt, [] and c-jun [] ) and negative regulators (e.g., carnitine palmitoyltransferase 1A, [] stearoyl CoA desaturase 1, [] Smo, [] tristetraprolin, [,] and small ubiquitin-related modifier [SUMO]-specific protease 2 [] ) of hepatic FGF21 are involved in the adipose homeostasis, these hepatic genes transit signals to the adipose through modulating hepatic FGF21 expression, secretion, and stabilization

3 Magnesium ions also participate in muscle contraction, control neuronal excitability, and influence neurotransmitter cycling by regulating the transmembrane transport of other ions