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Decontamination efforts should be made after ensuring the airway, and antidotes such as NAC are initiated immediately in suspected paracetamol overdoses, even before serum levels confirm toxicity, to prevent irreversible liver damage [24, 25]

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Within AIA rats, TNF- enhances FLS growth, increases 7nAChR levels, and stimulates the ERK/Egr-1 pathway, while SIN mitigates these impacts by reducing FLS growth, 7nAChR levels, and ERK/Egr-1 pathway activation (92)