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Distinct endotypes of steroid-resistant asthma characterized by IL-17A(high) and IFN-(high) immunophenotypes: potential benefits of calcitriol

Similarly, Hosohata et al

Arch Biochem Biophys, 483: 229-235, 2009

Another limitation observed was that BA-LRA scores were biased toward P450-mediated bioactivation compared to drugs that form reactive CoA-thioesters or unstable acyl-glucuronides