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10 M DPI was used as a positive control for superoxide production, while 10 M doxorubicin was used as a positive control for H 2 O 2 generation

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Moreover, it is essential to investigate combination therapy, such as curcumin in conjunction with conventional treatments, and to conduct mechanistic research to elucidate pathways like Nrf-2 or PPAR-LXR-ABCA1

European League Against Rheumatism recommendations for the management of psoriatic arthritis with pharmacological therapies

The key molecular pathway identified involves the activation of the general control nonderepressible 2 (GCN2) kinase, leading to the phosphorylation of eukaryotic initiation factor 2 alpha (eIF2) and the upregulation of ATF4