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Food Chem 340:127876

Using in vivo studies, they demonstrated that a B vitamin deprivation diet led to hyperhomocysteinemia, an imbalance of SAM/SAH, PS1, and BACE upregulation, each of which increased A deposition in TgCRND8 mice [142, 143]

XBP-1 deficiency in the nervous system protects against amyotrophic lateral sclerosis by increasing autophagy

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The surplus of lipids not only provides the energy supply for tumor cells but also fosters the proliferation and metastasis of these cells while instigating signal transduction and epigenetic occurrences (138, 139)