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Wang L, Yin YL, Liu XZ, Shen P, Zheng YG, Lan XR, Lu CB, Wang JZ, et al

Topical evidence for skin improvement is strong at the mechanism level (collagen, elastin, GAG synthesis upregulation in fibroblasts) and moderate at the human cosmetic-trial level (Leyden 2002 conference abstract

doi: 10.1016/s0361-9230(98)00091-4, 55

doi: 10.1016/j.fertnstert.2016.07.1075 22

60 mM for coronary) and endothelial integrity was confirmed by 50% relaxation to acetylcholine (10 M) in arteries contracted with U46619 (concentration to achieve 7080% of maximal KCl response)