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10.1080/19420862.2016.1156829 57 DrachamC

Schoenenberger, G.A

Seeck, M

DSIP was tested for its antinociceptive effects in mice and rats

"Centenarians display plasma MOTS-c concentrations significantly higher than age-matched peers, a pattern that closely resembles levels found in individuals decades younger suggesting preserved mitochondrial signaling as a hallmark of exceptional longevity." The connection to cellular senescence deserves further attention here