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DSIP crosses the blood-brain barrier freely an unusual property for a peptide of its size via a non-competitive, non-saturable passive mechanism whose physicochemical determinants (lipophilicity, charge, molecular weight, and protein-binding) are now well characterised

doi:10.1021/acs.jmedchem.5b00726 Hay DL, et al

Description: Corticotropin Releasing Hormone Binding Protein Human Recombinant Corticotropin releasing hormone binding protein, CRF-BP, CRH-BP, CRF-binding protein

Can BPC-157 cause liver damage

Reports of short-term tolerance exist in small observational settings, yet these reports lack randomized control, large populations, and multi-year follow-up