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Mitochondrial lipid peroxidation was determined using the ratiometric fluorescent probe MitoPerOX (Cayman Chemical, 18798) according to the manufacturers protocol

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These master antioxidants are formed in our cells, helping protect the body from oxidative stress and free radicals

However, it is important to note that while the high energy demand theory is widely accepted, in vivo evidence directly confirming it as the primary or sole cause of neuronal loss in PD remains incomplete, as other factors such as calcium dyshomeostasis and iron metabolism abnormalities are also intertwined [20, 21]

Thus, Quer, as an activator of the GSH system, is a promising natural small molecule for the treatment of cardiac injury