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45 Common oral glucose-lowering agents, including metformin, 46 dapagliflozin, 47 and glucagon-like peptide-1 receptor agonists (GLP-1RAs), 48 have demonstrated efficacy in mitigating DKD-associated senescence

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AlCl3+ high-dose L-carnitine group showed: Cortex and complete hippocampus of caspase 3: a): Cortex showed negative cytoplasmic reactivity (arrow) for Caspase-3 in cerebral cortex, (b, c, d, e, f): Showed Hippocampus with negative cytoplasmic reactivity (arrow) for Caspase-3 in CA1, CA2, CA3, and in DG H&E