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In a meta-analysis that pooled findings from six randomized controlled trials with a total of 301 participants, vitamin D was found to reduce migraine frequency, number of days affected by migraine, and migraine-related disability scores (Hu 2021)

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61 In another MRI study by Markku Vornanen et al., it was shown that in well selected population (n = 14) of non-pediatric patients (from n = 122) with thoracolumbar burst fractures or flexion distraction injuries, in 11 patients degeneration with signal loss on MRI, one or both discs adjacent to a fractured vertebra occurred, and, in all concerned discs, a decreased height was evident after long segment instrumentation and later implant removal