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HPII can be differentiated from HPI on the basis of urinary P5C levels, but the gold standard for diagnosis is still genetic testing [19]

2a/ESM Fig

Using Formula I as a generic formula, for this particular analog, R1=hexanoyl

However, on the way to that long-term predicted change, populations of that species may experience numerous increasingly extreme weather events that could produce much higher (or lower) temperature excursions that fall outside the survivable temperature range