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Uptake of environmental toxicants by the locus ceruleus: a potential trigger for neurodegenerative, demyelinating and psychiatric disorders

Jed Fuhrman Office AHF 211 Office Phone (213) 740-5757 Research & Practice Areas Marine Microbial Ecology, Biological Oceanography, Microbial Diversity, Human Pathogens in Marine Environments Center, Institute & Lab Affiliations Wrigley Institute for Environmental Studies, Education Ph.D

HIF-1 can regulate the expression of VEGF gene under hypoxic stimulation (212), which is related to the adaptation of RA synovial membrane to the hypoxic microenvironment (211)

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Luckily, in most people, aldehyde dehydrogenase immediately breaks down acetaldehyde, ultimately turning it into into compounds such as acetate, which cells commonly use in metabolism