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Safe for multi-dose vials

[7] [9] Patients with a history of oxalate nephrolithiasis (kidney stones) or hyperoxaluria should avoid high-dose vitamin C administration, as ascorbic acid is metabolized to oxalate, which may precipitate stone formation or exacerbate renal impairment

Sleep changes Less consistently reported

Your doctor may include B12 infections as part of the treatment for conditions that are associated with poor nutrition, malabsorption of vitamin B12 from the intestines or deficiency of this vitamin due to obesity, vegetarian diets, or macrobiotic diets

Those most at risk of a Vitamin B12 deficiency include elderly people, those who follow a vegetarian or vegan diet, people who have had intestinal surgery and people with diseases of the gut, such as Crohn's Disease or Celiac Disease