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Kidney physiology and susceptibility to acute kidney injury: implications for renoprotection

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however, PQQox can catalyze the non-enzymatic oxidation of the epsilon amine function of lysyl groups to aldehydic functions in proteins, such as elastin and collagen, and the oxidation of pyridoxamine and pyridoxamine-5-phosphate to pyridoxal and pyridoxal-5-phosphate [12]

Among these, topiramate has been clinically proven to be effective for migraine prevention and is recommended as a first-line treatment (Irimia et al., 2012)

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