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Several new therapeutic agents are currently under investigation for AIH, including B-cell activating factor (BAFF) inhibitors, low-dose IL-2, Toll-like receptor-4 antagonists, pre-implantation factor, and inflammasome inhibitors among others [132]

S., Agarwal, A., Mohanty, G

Depending on the final federal register language, additional peptides from the 2023 restricted list such as Selank, Semax, or KPV may also fall within scope

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Altogether, astrocytic purinergic receptors represent attractive therapeutic targets due to their early involvement in disease pathogenesis and in regulating key processes such as inflammation, neuronal excitability, and interstitial solute clearance