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Replace In this stage, we focus on restoring what the digestive system needs to function properly

Conversely, recombinant TGF-3 therapy like avotermin has found widespread success in reducing scarring following surgery with more organised ECM deposition [82]

And capsaicin was reported to upregulate Sirtuin 1 (SIRT1) levels through TRPV1/[Ca 2+ ]i/Calcium-calmodulin-dependent protein kinase II (CaMKII)/AMP-activated protein kinase (AMPK) pathway and inhibit intermittent high glucose-mediated endothelial cell senescence [224]