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DMEM uses a sodium bicarbonate buffer system (3.7 g/L), and therefore requires a 510% CO 2 environment to maintain physiological pH

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In this regard, an increased intake in choline in animal models of Down syndrome has shown a positive cognitive effect in several visual attention tasks, affective and neural functioning and the normalization of hippocampal neurogenesis [193,194,195]

10.1371/journal.pbio.2006203 27 FengL.ZhaoK.SunL.YinX.ZhangJ.LiuC.et al (2021)

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